Early and late endocrinologic complications of the hematopoetic stem cell transplantation performed for hematologic malignancies
نویسندگان
چکیده
منابع مشابه
Stem Cell Transplantation for Hematologic Malignancies
Histocompatibility in transplantation is governed by the products of the human leucocyte antigen (HLA) genes encoded within the major histocompatibility complex (MHC) on chromosome 6p21. HLA antigens define tissue type and are inherited en bloc in classical Mendelian fashion. Genotypically identical siblings inherit the same paternal and maternal chromosome 6. Haploidentical relatives share one...
متن کاملHematopoetic stem cell transplantation in children.
Bone marrow transplantation is called hematopoetic stem cell transplantation (HSCT), since peripheral blood and umbilical cord blood can also be used as sources of stem cell currently. In children, bone marrow transplantation is used as a definite treatment method in many diseases including hemoglobinopaties, immune deficiencies, bone marrow failure and congenital metabolic diseases in addition...
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BACKGROUND Hematopoetic stem cell transplants (HSCT) are discussed as treatment options for patients with solid tumors. Transplant numbers have changed substantially over the last decade, few controlled studies are available and different opinions prevail. Objective information on current practice is needed. PATIENTS AND METHODS Data from 27 902 HSCT for solid tumors (2% allogeneic, 98% autol...
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Telomeres are specific nucleoprotein structures at the ends of eukaryotic chromosomes. Telomeres and telomere-associated proteins maintain genome stability by protecting the ends of chromosomes from fusion and degradation. In normal somatic cells, the length of the telomeres gradually becomes shortened with cell division. In tumor cells, the shortening of telomeres length is accelerated under t...
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BACKGROUND Allogeneic hematopoietic stem cells transplantation (HSCT) is a curative intervention in patients with haematological malignant and non-malignant diseases, immunodeficiency, autoimmune, and other genetic diseases. Early complications are complications that are occurring in the first 100 days, while complications arising after the 100th day of transplantation belong to late complicati...
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ژورنال
عنوان ژورنال: Journal of Clinical and Experimental Investigations
سال: 2012
ISSN: 1309-6621
DOI: 10.5799/ahinjs.01.2012.01.0134